Pro-collagen ‘memory foam’ moisturizer designed to work with your skin's natural repair cycle, delivering continuous firming benefits in a cocoon of hydration while you sleep and simultaneously fortifying your skin's protective barrier.
50 ml / 1.7 fl oz
Benefits
Smooths and improves elasticity while you sleep
Helps firm and support skin's structure
Works with your skin's natural repair cycle to help soothe and reduce puffiness
Repairs skin barrier
Deeply hydrates
Claims
Dermatologist tested
Fragrance free
Cruelty free
Gluten free
Vegan
Appropriate for all skin tones
Made in USA of global materials
Evaluated as part of an ongoing clinical study, in partnership with Howard University Department of Dermatology
How to Use
Apply nightly as the last step of your routine, gently smoothing over face and neck.
In an 8-week clinical study at Howard University, participants using Circadian Cream experienced improved skin hydration, moisture retention and wrinkles
This overnight collagen seal cream is a game changer. I put it on as the last step in my nightly skin routine. In the morning I notice my skin is evenly smooth and plump with a nice subtle firmness. I really appreciate that it doesn't make my skin feel tight at all but rather moisturized and sealed. 10 out of 10.
Skin Type Sensitive
Daysha H.
Verified Buyer
Rated 5 out of 5 stars
4 weeks ago
The best!
Love this cream! My face is happy.
Skin Type Normal
Keisha T.
Verified Buyer
Rated 5 out of 5 stars
1 month ago
Most Effective Skin Care Products
I happen to come across Mrs. James’ skincare routine youtube video in May 2025. I had been searching for something that would nourish my dry skin. I read up on the products/ingredients and customer reviews. After I got past the initial sticker shock, I decided to try all 3 products. I also purchased the cleanser and towelettes mentioned in that same video. Almost 3 months later, I can say that this is by far the best skin care line that I have used. I have extremely sensitive skin, and typically know with the first application whether something will work. My skin looks and feels amazing. The products are easily absorbed and leaves my skin feeling smooth and soft so much that I don’t always feel the need to wear foundation in order to obtain that flawless dewy look. Pigmentation on my cheeks has started clearing up, the skin around my eyes has completely smoothed out, and the texture and tone of my skin is beautiful. I can attest to experiencing all of the benefits mentioned for each product. I love the blue light protecting factor as I spend a lot of time in front of the screen working. A little goes a long way with these products. You don’t need to use a lot.
Skin Type Dry
Margareth C.
Verified Buyer
Rated 5 out of 5 stars
2 months ago
Perfection
No smell so far so good
Skin Type Dry
Glyniss F.
Verified Buyer
Rated 5 out of 5 stars
2 months ago
Approved
Aa a 65 yr old with a bathroom filled of skin products the combination of the products in reframe is just what my skin needed.
A medical procedure where a small sample of tissue is removed from the body for examination under a microscope. It's used to diagnose various conditions or to identify abnormalities.
Clinical Study
A clinical study for skincare is a scientific research method that evaluates the safety and effectiveness of products, treatments, or ingredients under controlled conditions. These studies are designed to provide evidence-based results about how skincare products perform when used by real people. Clinical studies are not legally required and most brands opt out, due to cost, time, risk and marketing preference.
Consumer Perception Study
A consumer perception study for skincare is a type of market research that focuses on gathering subjective feedback from actual consumers about their experience using skincare products. Unlike clinical studies that emphasize objective measurements, consumer perception studies prioritize how users feel about and perceive the product's performance.
Fitzpatrick Scale
The Fitzpatrick scale is a numerical classification system used to categorize human skin color and its response to ultraviolet (UV) radiation. Developed in 1975 by Thomas Fitzpatrick, a Harvard dermatologist, it's widely used in dermatology, cosmetics, and skincare to determine appropriate treatments and product recommendations. The Fitzpatrick scale helps dermatologists assess skin cancer risk, determine appropriate laser treatment settings, guide sunscreen recommendations, and customize skincare regimens. In clinical studies, it's an essential tool for ensuring diverse participant selection and analyzing how treatments perform across different skin types.
Fitzpatrick Skin Types
The scale consists of six types:
Type I: Ivory skin that always burns, never tans
Type II: Fair skin that burns easily, tans minimally
Type III: Medium skin that sometimes burns, gradually tans
Type IV: Olive skin that minimally burns, tans easily
Type V: Brown skin that rarely burns, tans darkly
Type VI: Deep brown to black skin that never burns, always tans
Peer Reviewed
"Peer reviewed" in a dermatological clinical trial means that the study and its results have undergone evaluation by independent experts in dermatology before being published or presented. This review process is a critical quality control step that helps ensure the research is scientifically sound. It is a higher level of scientific credibility since the findings have been scrutinized and validated by objective third-party experts.
Research Gap
The diversity research gap in dermatology refers to the significant underrepresentation of diverse skin types and ethnicities in dermatological research and clinical studies. This gap has created disparities in how skin conditions are diagnosed, treated. For skincare brands, addressing this research gap represents both an ethical responsibility and a business opportunity. By conducting inclusive clinical testing that encompasses the full range of skin types and ethnicities, brands can develop more universally effective products while also contributing to closing this significant knowledge gap in dermatological science. This commitment to diverse research helps ensure products work effectively for all consumers while advancing more equitable skincare science.
White Paper
A white paper in dermatology is a specialized document that provides in-depth, evidence-based information about dermatological conditions, treatments, research findings, or clinical methodologies. For a skincare company, a dermatology white paper might present clinical study results for a product line, explain the scientific mechanism behind a proprietary ingredient, or discuss the effectiveness of specific formulations for different Fitzpatrick skin types.
